No deaths in the program were attributed to rosuvastatin, and no rhabdomyolysis occurred in patients who received 5 to 40 mg of rosuvastatin.

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rosuvastatin is an inhibitor of 3-hydroxy-3-methylglutaryl-coenzime a hmg-coa reductase, the enzyme that catalyzes the conversion of hmg-coa to mevalonate, a limiting agent of the biosynthesis of cholesterol and it is therefore used to treat and prevent hypercholesterolemia, to promote the regression of atherosclerotic plaque and to prevent cardiovascular events.

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the primary use of rosuvastatin is for the treatment of dyslipidemia.

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in other respects, the safety profile of rosuvastatin was similar in children and adolescents compared to adults.

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