The histomorphometric parameter mineralizing surface, an index of bone turnover, was assessed based upon baseline and post-treatment biopsy samples from 21 treated with placebo and 23 patients treated with actonel sodium 5 mg.

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remember, the drugs which have been developed for the treatment of osteoporosis fosamax, actonel, evista, boniva, miacalcin, etc, are very good drugs for routine osteoporosis, but they were not designed to work in patients with parathyroid tumors, and they do not.

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compared to the actonel sodium 5 mg daily regimen, actonel sodium 150 mg once-a-month resulted in a slightly higher incidence of hypocalcemia at the end of the first month of treatment.

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The duration of the trials was one year, with 173 patients exposed to placebo and 176 patients exposed to actonel 5 mg daily.

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